AniView100 In vivo Animal Imaging System

Date:2020/3/7



The AniView100 Multi-mode  In vivo Animal Imaging System is a high-sensitivity, multi-mode animal living imaging system launched by Guangzhou Biolight Biotechnology Co., Ltd.  It adopts a first-level back-thinning, back-sensitive ultra-low temperature CCD camera with extremely high detection sensitivity, and a specially designed dark box can effectively avoid the influence of external light and cosmic rays on imaging. High-power full-wavelength halogen lamp excitation light source combined with a sophisticated and complex embedded ring-shaped global excitation light source and Dual universal point-shaped excitation light source optical system, coupled with advanced spectral conversion capabilities and filter combinations, greatly improve the fluorescence signal The specificity and greatly shorten the exposure time and reduce the effect of the experiment on mice.

Details

Advantages:

1.Super sensitive


Fully enclosed anti-interference dark box, while avoiding the impact of external light sources and cosmic rays on the photo, with zero defect, scientific-grade high-sensitivity back thinning, back-sensing cold CCD camera, greatly improve the imaging sensitivity. AniView100 can detect <100 luciferase-labeled cells or <10ng FITC in mice. Accurate experimental results and reduce experimental errors.


2. Low background

The Fluorescence Imaging Module is equipped with a 150W full-wavelength halogen lamp, a variety of freely combustable filters, in-line global illumination and a dual universal point-like fluorescence illumination unit, combined with advanced spectral conversion capabilities and fluorescent self-luminous interference subtraction. Fully meet the "low background" requirements of fluorescence imaging experiments.


3. Large field of view

The perfect combination of AniView100's wide-angle lens and hardware structure creates an extremely large imaging field of view, which can achieve simultaneous imaging of 6 mice or 1 rabbit (270mm × 270mm). And the software presets the experimental scheme, which can automatically adjust the size of the field of view according to the sample size and autofocus to achieve one-click imaging.


4. Humanization

The user-friendly software can automatically control the instrument stage lifting, temperature and various light sources; a variety of fluorescence intensity expression options, quantitative analysis functions, direct output of experimental reports, simplify instrument operation, saving you time.


5. Multifunctional

The instrument is also equipped with multiple flange interfaces and power sockets, which can be connected to animal temperature control bed, X-ray animal structure imaging module, gas anesthesia module, up-conversion fluorescent UCNPs detection module, microscope, etc., which can be quickly selected according to experimental requirements. Modules, experimental methods are more diverse and more powerful.

Application range:

Cancer and anticancer drug research, immunology and stem cell research, apoptosis, pathological mechanism and virus research, gene expression and protein interaction, transgenic animal model construction, drug efficacy evaluation, drug selection and pre-clinical testing, drug formulation With dose management, oncology applications, biophotonics detection, etc.

Case 1: Oncology application

AniView100 can directly and quickly measure tumor growth and metastasis in various cancer models, and can quantitatively detect tumors in situ, metastases and spontaneous tumors without trauma. It is possible to distinguish normal cancer cells from apoptotic cancer cells at an early stage, and it is convenient to observe the tumor metastasis and recurrence.

Luciferase labeled tumor metastasis model

Case 2: Application of animal gene function research

AniView100 can directly reflect the spatial and temporal distribution of cell or gene expression, thereby understanding the biological functions of specific genes in the body, such as function and interaction, and embryo development.

GFP transgenic mice

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